Effects of head down tilt on cerebral circulation

Dose-dependent effects of head down tilt on cerebral circulation - Dose-dependent effects of head down tilt on cerebral circulation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000036541

Enrollment

Registered

2019-04-18

Start date

2019-05-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults

Interventions

Head-down tilt (-30 degrees) position for 10 min Head-down tilt (-10 degrees) position for 10 min Horizontal position, (0 degree) for 10 min

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Healthy adults consented to participate in the study Cerebral blood flow velocity signals in the middle cerebral artery can be obtained by transcranial Doppler ultrasonography.

Exclusion criteria

Exclusion criteria: Not satisfy selection criteria noted above

Design outcomes

Primary

Measure	Time frame
Gain, coherence and phase between arterial blood pressure and cerebral blood flow variabilities in the spine position, and head down tilt position (-10, -30 degrees)	—

Secondary

Measure	Time frame
Cerebral blood flow velocity, pulsatility index, blood pressure variability, respiratory indexes, intracranial pressure, baroreflex function, heart rate variability, skin blood flow	—

Countries

Japan

Contacts

Public ContactTomokazu Kato

Nihon University School of Medicine Division of Hygiene, Department of Social Medicine

kato.tomokazu@nihon-u.ac.jp03-3972-8111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026