Chronic constipation siagnosed by RomeIV criteria
Conditions
Interventions
alosenn
magnesium oxide
placebo
Sponsors
Hyogo College of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Chronic constipation patient aged 20-74 years and diagnosed according to the RomeIV criteria
Exclusion criteria
Exclusion criteria: Candidates are excluded if they prescribe drug for constipation in hospital or use the over the counter medicines for constipation Everyday Candidates are excluded if they cannot use the over the counter medicines for constipation until fourteen days from consent of this study Candidates are excluded if any of the following are evident: current evidence of renal dysfuncti or cardiac disturbance or hypermagnesemia Secondary constipation candidates are excluded Candidates are excluded if take a madecine of the proton pump inhibitor or the potassium-competitive acid blocher Female patient could not be pregnant,as confirmed by a negative serum pregnancy test at the baseline visit
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| overall improvement over the 4-week study period | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.spontaneous bowel movement (SBM) 2.complete spontaneous bowel movement (CSBM) 3.stool form 4.abdominal symptom 5.quality of life (QOL) | — |
Countries
Japan
Contacts
Public ContactToshihiko Tomita
Hyogo College of Medicine Division of Gastroenterology,Department of Internal Medicine
Outcome results
None listed