Target population is young healthy women with menstrual and premenstrual disorder without g gynecological treatment.
Conditions
Interventions
Whole grain soybean milk, total energy 88 kcal/portion -12 week intervention -Administration, one portion (125 mL) per day
Milk protein and coco-oil substituted soybean free '
soybean-like'
beverage (88 kcal/portion) -12 week intervention -Administration, one portion (125 mL) per day
Sponsors
Human Ecology Department, Graduate School of Wayo Women's University
Biwako Research Institute, Otsuka Foods Company, Ltd.
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: -Healthy women with the frequency of soybean-products consumption less than twice a week -The equol content in urine less than 5.0 micro-mol/g creatinine at isoflavone loading test
Exclusion criteria
Exclusion criteria: -Allergy for soybean and/or milk -Gly m4 type Oral allergy -Pregnant women -Patients receiving treatment for chronic diseases -Women disqualified by a physician in charge -Subjects who receiving medical treatment by Dysmenorrhea or premenstrual syndrome
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| -The comparison of equol in urine between initial and final samples after 12 weeks intake. -Improvement of menstrual and premenstrual major disorder during intake. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Time course study of equol content in urine. 2) Questionnaires on menstrual and premenstrual disorder (physical or mental aspects). 3) Relation of Microbialflora in intestine to outcomes. | — |
Countries
Japan
Contacts
Public ContactHadjime NAKAJIMA
Wayo Women's University Human Ecology Department, Graduate School
Outcome results
None listed