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Randomized controlled trial of lactobacillus medications to treat bacterial vaginosis in infertility patients

Randomized controlled trial of lactobacillus medications to treat bacterial vaginosis in infertility patients - The trial of lactobacillus medication

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000036429
Enrollment
200
Registered
2019-04-06
Start date
2019-04-06
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bacterial vaginosis

Interventions

The patients who are diagnosed with bacterial vaginosis are treated with antibiotics. (Metronidazole or amoxicillin hydrate) The patients with the results of the vaginal culture test are Nugent score

Sponsors

Kamiya Ladies Clinic
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1,The patients who voluntarily provide written informed consent to participate in the study and comply with all study procedures 2, The patiens with general infertility 3, 45 years old or younger 4, The patients result of vaginal culture is Nugent score 3 or more

Exclusion criteria

Exclusion criteria: 1)Pregnant woman 2)The patient who was not able to use the ethical drug by rule. 3)The patient with the underlying disease 4)The patient who is given a steroid and an immunosuppressive drug 5)The patient using a Intrauterine device. 6)The patient after using pill in a previous menstrual cycle. 7)Case with urinary tract infection.

Design outcomes

Primary

MeasureTime frame
The proportion of the improvement of Nugent score and the rate of increasing Lactobacillus in the patients' vagina

Secondary

MeasureTime frame
1, The proportion of patients experiencing improvement of the clinical pregnancy rate after treatment of lactobacillus medication 2, The proportion of patients experiencing improvement of the ongoing pregnancy rate after treatment of lactobacillus medication 3, The proportion of patients experiencing improvement of the miscarriage rate after treatment of lactobacillus medication

Countries

Japan

Contacts

Public ContactMiho Kawamata

Kamiya Ladies Clinic Reproductive Center

mihok@lemon.plala.or.jp011-231-2722

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026