EFFICACY OF 1% SODIUM CROMOGLYCATE GEL LOCAL DRUG DELIVERY AS AN ADJUNCT TO SCALING AND ROOT PLANING IN THE TREATMENT OF CHRONIC PERIODONTITIS: A CLINICAL STUDY.

EFFICACY OF 1% SODIUM CROMOGLYCATE GEL LOCAL DRUG DELIVERY AS AN ADJUNCT TO SCALING AND ROOT PLANING IN THE TREATMENT OF CHRONIC PERIODONTITIS: A CLINICAL STUDY. - EFFICACY OF 1% SODIUM CROMOGLYCATE GEL LOCAL DRUG DELIVERY AS AN ADJUNCT TO SCALING AND ROOT PLANING IN THE TREATMENT OF CHRONIC PERIODONTITIS: A CLINICAL STUDY.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000036356

Enrollment

Registered

2019-03-31

Start date

2017-05-09

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic periodontitis

Interventions

Patients were randomly allocated in test and control sites. In the Test sites 1% sodium cromoglycate gel was delivered after scaling and root planing. Plaque index (PI),Relative Attachment Level (RAL)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Willingness to comply with the study protocol. Subjects in the age group more than or equal to 30 years without any systemic disease. More than or equal to 20 teeth present in the oral cavity. Patients with moderate chronic periodontitis having more than or equalto 2 interproximal sites with Clinical Attachment Loss more than or equal to 4 mm not on the same tooth and interproximal sites with Probing Pocket Depth more than or equal to five mm also not onthe same tooth each tooth site in two different quadrants.

Exclusion criteria

Exclusion criteria: Patient with any systemic disease. Patient with aggressive periodontitis. Users of tobacco in any form. Patient on systemic mast cell stabilizer therapy. Patient who had undergone periodontal therapy in previous 6 months. Individual with known or suspected allergy to mast cell stabilizer group. Pregnant or lactating women. Patient with history of Antibiotic therapy for any chronic inflammatory condition with in six months prior to study. Patient not willing to give written consent.

Design outcomes

Primary

Measure	Time frame
Relative Attachment level (RAL) at baseline, 1 month and 3 months	—

Secondary

Measure	Time frame
Plaque Index (PI), Modified Sulcus Bleeding Index (mSBI), Probing Pocket Depth (PPD) at baseline, 1 month and 3 months. Visual Analogue Scale (VAS) recorded at 3rd day	—

Countries

Asia(except Japan)

Contacts

Public ContactDr. Nitanshi khare

School of Dental Sciences, Sharda University Department of Periodontology

nitanshi.khare@gmail.com+918010641510

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026