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Inhibitory effects of amino acids against increasing in serum uric acid levels induced by purine ingestion: a randomized, single-blind, crossover study

Inhibitory effects of amino acids against increasing in serum uric acid levels induced by purine ingestion: a randomized, single-blind, crossover study - Effects of amino acids against increasing in serum uric acid levels induced by purine ingestion

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000036345
Enrollment
16
Registered
2019-04-01
Start date
2019-04-08
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults

Interventions

Ingestion of 100 ml water contained 0.2g purine bodies Ingestion of 100 ml water contained 0.2g purine bodies and essential amino acid Ingestion of 100 ml water contained 0.2g purine bodies and non-es

Sponsors

Asahi Quality and Innovations, Ltd.
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 1.20 - 64 years old 2.Healthy male 3.Type of decrease in urinary excretion of uric acid (<0.48 mg/kg/h)

Exclusion criteria

Exclusion criteria: 1.Volunteers with a history of diabetes, liver, renal, and heart 2.Volunteers who conducting exercise or diet therapy 3.Volunteers who taking a medicine daily 4.Volunteers with a history of severe diseases ingested medicines 5.Volunteers with a history of drug or food allergy 6.Volunteers with routine use medicines or dietary supplements concerning uric acid-lowering effect 7.Volunteers who participated other clinical trial within three months 8.Volunteers with hepatitis B antigen 9.Volunteers who are judged not to be appropriate as the subjects in this trial

Design outcomes

Primary

MeasureTime frame
Serum uric acid concentration

Secondary

MeasureTime frame
Excretion amount of urinary uric acid, urinary pH

Countries

Japan

Contacts

Public ContactShunji Oshima

Asahi Quality and Innovations, Ltd. Core Technology Laboratories Principal Researcher

shunji.oshima@asahigroup-holdings.com0297-46-9351

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026