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The Relationship between Dose of Fentanyl and Postoperative Nausea and Vomiting in Patients with Fentanyl-based Intravenous Patient-controlled Analgesia: A Retrospective Cohort Study with 450 Patients

The Relationship between Dose of Fentanyl and Postoperative Nausea and Vomiting in Patients with Fentanyl-based Intravenous Patient-controlled Analgesia: A Retrospective Cohort Study with 450 Patients - The Relationship between Dose of Fentanyl and Postoperative Nausea and Vomiting in Patients with Fentanyl-based Intravenous Patient-controlled Analgesia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000036303
Enrollment
500
Registered
2019-03-27
Start date
2018-10-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients who received IV-PCA following a spine surgery or an upper limb surgery

Interventions

None listed

Sponsors

Department of Anesthesiology, Kumamoto Central Hospital, Kumamoto, Japan
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients who received IV-PCA following a spine surgery or an upper limb surgery between January 2012 and September 2018 were eligible for this study.

Exclusion criteria

Exclusion criteria: Patients who did not receive IV-PCA following a spine surgery or an upper limb surgery between January 2012 and September 2018 were not eligible for this study.

Design outcomes

Primary

MeasureTime frame
Postoperative nausea and vomiting observed within 48 hours after the orthopedic surgical procedure

Secondary

MeasureTime frame
Age, gender, BMI, alcohol drinking status, smoking status, surgical duration, anesthesia duration, intraoperative fentanyl and remifentanil dose, and postoperative fentanyl concentration were analysed between PONV patients and non-PONV patients.

Countries

Japan

Contacts

Public ContactATSUSHI KOTERA

Kumamoto Central Hospital Department of anesthesiology

z250streetfighter@gmail.com096-293-0555

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026