Multi-center Prospective Clinical Study for Efficacy and Safety of Laparoscopic Double-Flap Reconstruction on Anti-reflux Potential to the Esophagus after Surgery

Multi-center Prospective Clinical Study for Efficacy and Safety of Laparoscopic Double-Flap Reconstruction on Anti-reflux Potential to the Esophagus after Surgery - lD-FLAP Study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000036191

Enrollment

Registered

2019-05-01

Start date

2019-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric cancer

Interventions

Laparoscopic proximal gastrectomy with lymphadenectomy followed by double-flap reconstruction

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Histologically diagnosed with gastric cancer. 2) Diagnosed with T1N0 according to Japanese Classification of Gastric Carcinoma (the 15th edition). 3) Tumor is located mainly in the upper stomach and proximal gastrectomy is considered oncologically appropriate. 4) Patients who can give written informed concent.

Exclusion criteria

Exclusion criteria: 1) Pregnant women or women with a possible pregnancy. 2) Patients who are otherwise judged by the investigator as unsuitable for enrollment.

Design outcomes

Primary

Measure	Time frame
Incidence of reflux esophagitis at 1 year after surgery	—

Secondary

Measure	Time frame
Incidence of anastomosis-related complications such as leakage, stricture and bleeding	—

Countries

Japan

Contacts

Public ContactShinji Kuroda

Okayama Unisversity Gastroenterological Surgery

shinkuro@okayama-u.ac.jp086-235-7257

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026