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Combination effect of exercise instruction and biologics on rheumatoid arthritis patients. -a randomized controlled trial-

Combination effect of exercise instruction and biologics on rheumatoid arthritis patients. -a randomized controlled trial- - Combination effect of exercise instruction and biologics on rheumatoid arthritis patients. -a randomized controlled trial-

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000036182
Enrollment
60
Registered
2019-03-13
Start date
2016-04-05
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rheumatoid arthritis

Interventions

We conducted guidance on living behavior in the control group. We instructed walking and standing sitting exercise in addition to living action instruction to the exercise instruction group. We conduc

Sponsors

Nagasaki University Graduate School of Biomedical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.RA diagnosed according to ACR/EULAR2010 revised criteria 2.RA patient who treated with Bio for the first time 3.Age<80 years old 4.Patients for whom written consent was obtained 5.Patients with class I to III of ACR functional classification 6.Patients who have been taking antirheumatic drugs (DMARDs) for the past 3 months 7.Patients who can walk for 10 minutes or more 8.Patients who can fully answer the questionnaire

Exclusion criteria

Exclusion criteria: 1.Patients judged by the attending physician as inappropriate for research 2.ACR functional classification class IV patients 3.Patients with high degree of joint deformity 4.Patients whose treatment for rheumatoid arthritis changed during the study period

Design outcomes

Primary

MeasureTime frame
knee extension muscle strength and 6 minute-walk test before and 3 months after the introduction of biological agents

Secondary

MeasureTime frame
DAS28-CRP,C-reactive protein,Erythrocyte sedimentation rate,White blood cell,Swollen joint number,Tender joint number,Visual Analogue Scale,Grip,Pinch strength,modified Health Assessment Questionnaire(mHAQ),MOS36-Item Short-Form Health Survey(SF-36)

Countries

Japan

Contacts

Public ContactKaori Yoshida

Nagasaki University Graduate School of Biomedical Sciences Department of Locomotive Rehabilitation Science, Unit of Rehabilitation Sciences

yee.yahho.jessie@gmail.com095-819-7919

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026