rheumatoid arthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.RA diagnosed according to ACR/EULAR2010 revised criteria 2.RA patient who treated with Bio for the first time 3.Age<80 years old 4.Patients for whom written consent was obtained 5.Patients with class I to III of ACR functional classification 6.Patients who have been taking antirheumatic drugs (DMARDs) for the past 3 months 7.Patients who can walk for 10 minutes or more 8.Patients who can fully answer the questionnaire
Exclusion criteria
Exclusion criteria: 1.Patients judged by the attending physician as inappropriate for research 2.ACR functional classification class IV patients 3.Patients with high degree of joint deformity 4.Patients whose treatment for rheumatoid arthritis changed during the study period
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| knee extension muscle strength and 6 minute-walk test before and 3 months after the introduction of biological agents | — |
Secondary
| Measure | Time frame |
|---|---|
| DAS28-CRP,C-reactive protein,Erythrocyte sedimentation rate,White blood cell,Swollen joint number,Tender joint number,Visual Analogue Scale,Grip,Pinch strength,modified Health Assessment Questionnaire(mHAQ),MOS36-Item Short-Form Health Survey(SF-36) | — |
Countries
Japan
Contacts
Nagasaki University Graduate School of Biomedical Sciences Department of Locomotive Rehabilitation Science, Unit of Rehabilitation Sciences