Skip to content

Cardiac rehabilitation focused on physical function of acute decompensated heart failure

Cardiac rehabilitation focused on physical function of acute decompensated heart failure - PEARL study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000036123
Enrollment
80
Registered
2019-03-18
Start date
2019-03-18
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute decompensated heart failure

Interventions

1:Cardiac rehabilitation standard program for heart failure, 20-40 minutes per day, 5 days per week 2:Resistance training starting from low intensity(Start from 1RM 30%) 3:Ergometer starting from lo

Sponsors

Uwajima City Hospital Department of Rehabilitation
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1:60 years-old 2:Walkable before hospitalization 3:No life crisis due to terminal disease (cancer etc.) 4:With the exception of PCI, there are no plans for valve replacement, CABG, or other surgery 5:No severe dementia

Exclusion criteria

Exclusion criteria: 1:All evaluation items can not be extracted 2:Death during hospitalization 3:NT-proBNP < 400 pg/ml at admission 4:Cognitive dysfunction 5:Acute coronary syndrome 6:Significant myocardial ischemia during low-intensity exercise 7:Resting heart rate > 120/min 8:Acute infective endocarditis, myocarditis, and pericaritis 9:Presence of a recent hospitalization for heart failure (< 1 month) 10:Severe symptomatic aortic stenosis, mitral stenosis, and hypertrophic obstructive cardiomyopathy 11:Severe pulmonary hypertension 12:Intracardiac thrombus 13:Untreated life-threatening arrhythmia 14:Resting blood pressure > 180 mmHg 15:Ongoing orthopnea 16:Requiring high inotropic support 17:Patients with circulatory assist device 18:A therapeutic device (extracorporeal pacemaker), an intravenous drip is inserted in the inguinal neck 19:Patients with inadequate oxygenation 20:Patients with mechanical ventilation 21:History of aortic dissection, or presence of aortic aneurysm or aortic dissection 22:Patients with uncontrolled diabetes 23:Peripheral arterial disease (Fontain 3-4) 24:Recent embolism 25:Patients undergoing hemodialysis 26:Serum creatinine > 3.0 mg/dl 27:Severe anemia 28:Patients who are not suitable for participation at doctors discretion

Design outcomes

Primary

MeasureTime frame
Short Physical Performance Battery(Evaluation until the 5th hospital day and at discharge or between the 14th and 21th hospital days)

Secondary

MeasureTime frame
1:Grip strength, isometric knee extension strength, gait speed(Evaluation until the 5th hospital day and at discharge or between the 14th and 21th hospital days) 2:Timed Up & Go Test (TUG), single leg standing time, 6 minutes walking(Evaluation at discharge or between the 14th and 21th hospital days)

Countries

Japan

Contacts

Public ContactYuta Nakaya

Uwajima City Hospital Department of Rehabilitation

y.nakaya.pt@gmail.com0895-25-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026