Safety and efficacy of fecal microbiota transplantation from healthy volunteers for patients with primary sclerosing cholangitis

Safety and efficacy of fecal microbiota transplantation from healthy volunteers for patients with primary sclerosing cholangitis - Fecal microbiota transplantation for patients with primary sclerosing cholangitis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000036121

Enrollment

Registered

2019-05-01

Start date

2019-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary sclerosing cholangitis

Interventions

fecal microbiota transplantation from healthy volunteers

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with a chronic cholestasis who are diagnosed as PSC with the specific findings by MRCP or ERCP 2. Patients with chronic liver injury or compensated liver cirrhosis (Child Pugh score below 9 point) 3. Presence or absence of the PSC-related colitis does not matter for an entry 4. Patients elder than 16 years old who are consented in writing of the applicant

Exclusion criteria

Exclusion criteria: Patients with a decompensated cirrhosis (Child Pugh score upper 10 point)

Design outcomes

Primary

Measure	Time frame
The level of serum ALP at 1, 2, 4, 8, 12, and 24 weeks post FMT	—

Countries

Japan

Contacts

Public ContactNobuhiro Nakamoto

Keio University, School of Medicine Division of Gastroenterology and Hepatology

nobuhiro@z2.keio.jp+81-3-3353-1211

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026