acute pharyngeal tonsillitis
Conditions
Interventions
Amoxicillin was administered at a dose of 40 to 50 mg/kg/day with an upper limit of 1,000 mg/day, divided into onec-daily doses, for 10 days.
Amoxicillin was administered at a dose of 40 to 50 mg/kg/d
Sponsors
Juntendo University, Department of Pediatrics
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The study subjects were suspected of having acute pharyngeal tonsillitis due to Streptococcus pyogenes infection. Clinical diagnoses were made on the basis of reference symptoms, such as fever, sore throat, malaise, and headache with acute onset, whereas the physical findings that suggested the infection included prominent pharyngeal redness, tonsil swelling with exudate, and cervical lymphadenopathy. The study subjects underwent rapid antigen test using a throat swab and isolation culture tests, in which Streptococcus pyogenes was detected.
Exclusion criteria
Exclusion criteria: Patients with a history of penicillin allergies or those who received antibacterial drugs within the previous 4 weeks were excluded from this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quantitative PCR tests of pharyngeal swab samples collected three time points: during visit 1 (before the start of the treatment), visit 2 (1 to 3 days after the treatment), and visit 3 (9 to 11 days after the treatment) | — |
Secondary
| Measure | Time frame |
|---|---|
| The clinical course and result of culture tests after the treatment | — |
Countries
Japan
Contacts
Public ContactAkihiro Nakao
Juntendo University Department of Pediatrics
Outcome results
None listed