cardiac surgery, thoracic aortic surgery
Conditions
Interventions
None listed
Sponsors
Division of Anesthesiology and Critical Care Medicin, Tottori University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)patients over 20 years at the time of obtaining informed consent 2)patients scheduled to undergo total intravenous anesthesia 3)patients scheduled for cardiac surgery or thoracic aortic surgery using cardiopulmonary bypass
Exclusion criteria
Exclusion criteria: 1)patients scheduled to undergo maintenance by volatile anesthesia 2)patients undergoing surgery requiring general anesthesia within 3 months prior to obtaining informed consent 3)patients with respiratory dysfunction 4)patients with severe lung disease 5)patients with smoking history within 3 months before consent acquisition 6)diabetic patients with poor control 7)patients with severe liver disease 8)patients with severe kidney disease 9)patients who receive chemotherapy, radiation therapy, immunotherapy within 3 months prior to obtaining informed consent 10)patients with systemically or locally active infections 11)highly obese patients 12)women who may be pregnant or have a possibility of pregnancy 13)patients who received study drugs or investigational drugs within 3 months prior to obtaining informed consent 14)patinets whom research investigator has determined to be inappropriate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| change in breath concentration of various biological gases during perioperative period(and change in exhaust gas concentration of cardiopulmonary bypass if possible) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) relevance of breath concentration of various biological gases and blood cytokines during perioperative period 2) relevance of breath concentration of various biological gases and blood ROS during perioperative period 3) relevance of breath concentration of various biological gases and biomarkers during perioperative period 4) relevance of breath concentration of various biological gases and various inspections during perioperative period 5) relevance of breath concentration of various biological gases and respiratory function during perioperative period 6) relevance of breath concentration of various biological gases and the cardiopulmonary bypass time during perioperative period 7) relevance of breath concentration of various biological gases and surgical contents during perioperative period 8) relevance of exhaust gas concentration of cardiopulmonary bypass and manufactured products of cardiopulmonary bypass during perioperative period | — |
Countries
Japan
Contacts
Public ContactKazumi Funaki
Tottori University Division of Anesthesiology and Critical Care Medicine
Outcome results
None listed