pretermn infants with respiratory insufficence with/without BPD
Conditions
Interventions
In the Study Group the physiotherapist will perform the technique of respiratory facilitation according to the reflex stimulations, experience already conducted in the neonates and modified for the pr
trigger point"
. Stimulating the trigger point will stimulate the respiratory activity by determining a compression on the stimulation side with consequent increase of the ipsilateral pulmonary ventilation / minute
Sponsors
Foundation Policlinico University A. Gemelli IRCCS, Catholic University of the Sacred Heart, Rome, Italy.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Preterm newborns with a gestational age less than or equal 30 weeks requiring invasive or non-invasive respiratory support.
Exclusion criteria
Exclusion criteria: - Outborn - Presence of major congenital malformations and/or genetic syndromes - Fetal hydrops - Inherited disorders of metabolism - Persistent Pulmonary Hypertension of Newborn - Severe circulatory shock (prolonged capillary filling, reduced strength of peripheral pulses, cool skin, lethargy, hypotension, oliguria, increasing lactate concentrations and metabolic acidosis) - Others unstable clinical conditions at the time of randomization for which the newborn can not perform the physiotherapy treatment required by the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of intubation and mechanical ventilation (MV) in the first week of life (excluding the intubation necessary for surfactant administration). This will represent the primary outcome for non-intubated infants in the delivery room. | — |
Secondary
| Measure | Time frame |
|---|---|
| - duration of MV during the hospital stay (only for the babies not intubated in the delivery room); - duration of O 2 -therapy during the hospital stay; - development of BPD (O 2 -dependence at 36 weeks of postmenstrual age); - incidence of atelectasis, - duration of non-invasive ventilation (NIV) during the hospital stay; - post-conceptional age attainment of complete respiratory autonomy (absence of any kind of respiratory support and oxygen); - length of the hospital stay - survival. | — |
Countries
Europe
Contacts
Public ContactGiovanni Vento
Foundation P. University A. Gemelli IRCCS Division of Neonatology
Outcome results
None listed