High-risk type Human papillomavirus (HPV) infection
Conditions
Interventions
Consumption of the functional food, AHCC(R) (3 g/day) for 4, 8 or 12 months. HPV testing will be conducted every 4 months, and intervention will cease upon confirmation of HPV negative result.
Consump
Sponsors
Hokkaido University Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: (a) Women with a cytology positive, high risk (hr) HPV positive result. (hrHPV includes type 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66 and 68) (b) Women aged 25-44 yrs (at registration) (c) Women who have provided informed written consent.
Exclusion criteria
Exclusion criteria: (a) Women diagnosed as having a histological diagnosis of Cervical Intraepithelial Neoplasia (CIN) grade 3 or worse, or who are in need of medical treatment (b) Women taking immuno suppressors such as steroids or biologics such as TNF-alpha (c) Women regularly taking immunostimulating supplements (d) Women with an uncontrolled progressive malignancy (e) Women suffering from any mental illness or mental symptoms which would make it difficult for them to participate in the study (f) Women who are unable to return for follow-up appointments. (g) Women who are or may be pregnant (h) Women who, for any other reason, are considered not suitable for participation by the investigators
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Persistent high-risk HPV infection | — |
Countries
Japan
Contacts
Public ContactSharon Hanley
Hokkaido University Hospital Gynecology
Outcome results
None listed