Respiratory infection
Conditions
Interventions
We recommend not to use antibiotics when all the followings are satisfied: 1) viral pathogen is proved by multiplex PCR, 2) patient is respiratory and circulatory stable, and 3) white blood cell count
13.0x103/mm3 and CRP <
5.0mg/dL. However, initiation or selection of antibiotics are decided according to physicians'
Sponsors
Osaka Women's and Children's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: We include patients admit to the PICU or high care unit with diagnosis of respiratory infection according to respiratory symptoms, hypoxia, or radiograph, and who required oxygen.
Exclusion criteria
Exclusion criteria: We exclude patients with immunodeficiency or who received therapeutic interventions for infections within the previous 1 month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of antibiotics administration within 14 days of admission. | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of mechanical ventilation, length of intensive care unit and hospital stay, mortality, complications due to antibiotics, and infectious complications within 28 days of admission. Proportion of broad antibiotics use, and cost of antibiotics within 14 days of admission. | — |
Countries
Japan
Contacts
Public ContactTakeshi Hatachi
Osaka Women's and Children's Hospital Department of Intensive Care Medicine
Outcome results
None listed