Physical Activity in Patients with Bronchial Asthma: a Multicenter study

Physical Activity in Patients with Bronchial Asthma: a Multicenter study - Physical Activity in Bronchial Asthma

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000035988

Enrollment

375

Registered

2019-02-25

Start date

2019-02-25

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bronchial asthma

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with asthma 1. Patients with asthma, 20 years or older, diagnosed by a history of episodic dyspnea, wheezing, chest tightness, cough and documented reversible airflow limitation and/or airway hyperresponsiveness. 2. Clinically stable asthma for at least 6 weeks 3. Individuals who can perform spirometry 4. Individuals who gave the written informed consent before the study Controls 1. Individuals 20 years or older without respiratory disease who gave the written informed consent

Exclusion criteria

Exclusion criteria: Patients with asthma 1. Respiratory disease other than asthma and COPD 2. Severe disease affecting walking and physical activity, such as trauma, lower limb paralysis, neurological disease, cardiovascular disease, acute infection Controls 1. Disease affecting physical activity 2. Abnormalities in chest radiograph and spirometry (%FVC < 80%, FEV1/FVC < 0.7)

Design outcomes

Primary

Measure	Time frame
Physical activity in patients with asthma and control subjects	—

Secondary

Measure	Time frame
1. Severe asthma and physical activity 2. Physical activity and clinical background factors, 6-minute walk test, asthma severity, control status, exacerbation history, and inflammatory biomarkers 3. Physical activity of the elderly asthma and its related factors 4. Obese asthma and physical activity, inflammatory markers 5. HADs score, BDNF and physical activity in asthma 6. Bone mineral density in asthma, physical activity, and inflammatory markers 7. Lung CT and physical activity, respiratory function including Mostgraph 8. Spinal muscles, physical activity, myostatin 9. Risk factors for future asthma exacerbation, deterioration of respiratory function, deterioration of QOL in patients with asthma 10. Risk factors of declining physical activity over time. 11. Association of asthma phenotype and endotype with physical activity. 12. Physical activity of asthma-COPD overlap, non-smoking and smoking asthma patients. 13 Influence of COVID-19 on asthma symptoms, QOL, physical activity, and exacerbation.	—

Measure

Time frame

1. Severe asthma and physical activity 2. Physical activity and clinical background factors, 6-minute walk test, asthma severity, control status, exacerbation history, and inflammatory biomarkers 3. Physical activity of the elderly asthma and its related factors 4. Obese asthma and physical activity, inflammatory markers 5. HADs score, BDNF and physical activity in asthma 6. Bone mineral density in asthma, physical activity, and inflammatory markers 7. Lung CT and physical activity, respiratory function including Mostgraph 8. Spinal muscles, physical activity, myostatin 9. Risk factors for future asthma exacerbation, deterioration of respiratory function, deterioration of QOL in patients with asthma 10. Risk factors of declining physical activity over time. 11. Association of asthma phenotype and endotype with physical activity. 12. Physical activity of asthma-COPD overlap, non-smoking and smoking asthma patients. 13 Influence of COVID-19 on asthma symptoms, QOL, physical activity, and exacerbation.

—

Countries

Japan

Contacts

Public ContactHiroshi Iwamoto

Graduate School of Biomedical Sciences Hiroshima University Department of Molecular and Internal Medicine

hir@hiroshima-u.ac.jp082-257-5196

Outcome results