N/A(healthy adults)
Conditions
Interventions
powder Dose: Take one package, two times a day Administration: Take one package before breakfast and dinner
Duration: 12 weeks Test material:Placebo Dose: Take one package, two times a day
Sponsors
Kyoto Prefectural University Of Medicine
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1)20yrs<=age<=65yrs 2)Male 3)Outpatients 4)6.0 mg/dl<=uric acid level <=7.9 mg/dl 5)Those who don't change living habits such as exercise, diet, etc. during the study period. 6) Those who received a full explanation of the procedures in the study, and informed consent was documented and signed.
Exclusion criteria
Exclusion criteria: 1) Those who are receiving medication and/or treatment such as hyperuricemia or gout. 2) Those who are under treatment of diseases (urinary stone, kidney stone, rheumatoid arthritis) which may influence the outcome of the study, or diseases (urinary tract infections, renal disorders, hypertension, diabetes) that are related to the study. 3)Those who are usually taking drugs and health foods affecting the study results (e.g. Chitosan, anserine, chrysanthemum polyphenols, lactic acid bacteria PA-3, supplement containing DNA / RNA, beer yeast, health food including vegetables (vegetable enzyme drink, green juice), etc.). 4) Whose diet is extremely irregular. 5) Those who are routinely drinking a large amount of alcohol. 6) Those who are habitually exercising such as marathon. 7) Currently, exercise therapy and diet therapy are performed/ planning to under the supervision of a physician . 8) serious heart disease [heart failure, myocardial infarction, myocarditis, etc.] liver disease [liver failure symptoms (fulminant hepatitis ),patients with cirrhosis of the liver, liver tumor], renal disease [nephrotic syndrome, renal failure (acute and chronic), uremia, merged, etc. hydronephrosis] 9) Those who have participated in other clinical trials within before consent get one month, and those who are currently participating in other clinical trials. 10) At the physician's judgment, who are determined that there is a possibility that either increased risk to the subject, or sufficient data not obtained.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum uric acid level | — |
Secondary
| Measure | Time frame |
|---|---|
| Urine dithiocarbamates concentration, Blood carotenoid concentration, Variety and ratio of bacteria in stool, Urine uric acid level / urinary creatinine level ratio. | — |
Countries
Japan
Contacts
Public ContactTomohisa Takagi
Kyoto Prefectural University of Medicine Department of Gastroenterology and Hepatology
Outcome results
None listed