Whether the lactate transport carrier is a biomarker for type 2 diabetes?

Whether the lactate transport carrier is a biomarker for type 2 diabetes? - Whether the lactate transport carrier is a biomarker for type 2 diabetes?

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000035924

Enrollment

100

Registered

2019-02-18

Start date

2014-05-08

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type2 diabetes

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Aged 20 years or older at the time of acquiring written informed consent of clinical research. (2) Diabetes patient diagnosed by the report of the Japan Diabetes Society Committee on the classification and diagnostic criteria of diabetes mellitus.

Exclusion criteria

Exclusion criteria: (1) Patients diagnosed as type1 diabetes, or a pancreas-associated autoantibody such as glutamic acid decarboxylase antibody was positive. (2) Patients diagnosed as respiratory failure or serious liver failure. (3) Patients who were judged inappropriate as the subject by the research director.

Design outcomes

Primary

Measure	Time frame
Correlation between plasma lactate, alanine and known diabetes marker (fasting blood glucose, HbA1c, insulin secretion ability etc.).	—

Secondary

Measure	Time frame
1. Correlation between plasma lactate, alanine and clinical information (age, sex, body weight, BMI, renal function, TG, LDL, HDL etc.). 2. Differences in the frequency of polymorphisms of diabetes-related genes in MCT 1, 4, 11 and the relationship between lactate and alanine and known diabetes markers.	—

Countries

Japan

Contacts

Public ContactIssei Higuchi

Hokkaido University Hospital Department of Pharmacy

i-higuchi@huhp.hokudai.ac.jp011-706-3455

Outcome results