Skip to content

Study for Autologous Blood-Derived Fibrin Gel (CGF) in Root-end Resection

Study for Autologous Blood-Derived Fibrin Gel (CGF) in Root-end Resection - Utilization of Autologous Blood-Derived Fibrin Gel in Root-end Resection

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000035878
Enrollment
24
Registered
2019-02-15
Start date
2019-02-15
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Apical periodontitis

Interventions

CGF injection group non-injection group

Sponsors

Japanese Association for Dental Science
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients who are considered to be effective means of root-end resection for solving the main complaint of the patient and expectation of hope 2. Patients with good overall condition 3. Patients with platelet counts of 100,000 / mm 3 or more 4. Patients aged 20 to 70 5. The consent of research participation is obtained by the document

Exclusion criteria

Exclusion criteria: 1. Patients with malignant tumor complicated or having a history 2. Patients with abnormal gingival proliferation or having a history of abnormal gingival proliferation 3. Malignant tumor, premalignant lesion or finding that they are suspected by intraoral diagnosis 4. Patients under 20 or over 70 5. Other patients who are suffering from severe infectious diseases etc. Patients who are judged to be inappropriate for dental practitioners providing this regenerative medicine, etc. from the viewpoint of safety measures etc. to the person who manufactures the following items Consider taking the interview and examination. (A) Hepatitis B virus (HBV) (B) Hepatitis C virus (HCV) (C) Human immunodeficiency virus (HIV) (D) Human T cell leukemia virus type 1 (HTLV-1)

Design outcomes

Primary

MeasureTime frame
Dental cone-beam CT imaging at 6 months post operation

Secondary

MeasureTime frame
Measurement of lesion reduction ratio (dental X-ray photography every 3 months until 12 months post operation).Immediately after surgery, the presence or absence of pain, chest pain and apical tenderness during the follow-up period is judged

Countries

Japan

Contacts

Public ContactMasahiro Saito

Tohoku University Graduate School of Dentistry Division of Operative Dentistry

mssaito@dent.tohoku.ac.jp022-717-8340

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026