Apical periodontitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients who are considered to be effective means of root-end resection for solving the main complaint of the patient and expectation of hope 2. Patients with good overall condition 3. Patients with platelet counts of 100,000 / mm 3 or more 4. Patients aged 20 to 70 5. The consent of research participation is obtained by the document
Exclusion criteria
Exclusion criteria: 1. Patients with malignant tumor complicated or having a history 2. Patients with abnormal gingival proliferation or having a history of abnormal gingival proliferation 3. Malignant tumor, premalignant lesion or finding that they are suspected by intraoral diagnosis 4. Patients under 20 or over 70 5. Other patients who are suffering from severe infectious diseases etc. Patients who are judged to be inappropriate for dental practitioners providing this regenerative medicine, etc. from the viewpoint of safety measures etc. to the person who manufactures the following items Consider taking the interview and examination. (A) Hepatitis B virus (HBV) (B) Hepatitis C virus (HCV) (C) Human immunodeficiency virus (HIV) (D) Human T cell leukemia virus type 1 (HTLV-1)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dental cone-beam CT imaging at 6 months post operation | — |
Secondary
| Measure | Time frame |
|---|---|
| Measurement of lesion reduction ratio (dental X-ray photography every 3 months until 12 months post operation).Immediately after surgery, the presence or absence of pain, chest pain and apical tenderness during the follow-up period is judged | — |
Countries
Japan
Contacts
Tohoku University Graduate School of Dentistry Division of Operative Dentistry