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Effect of neuromuscular blockage status on intraoperative MEPs monitoring during spinal surgery: A retrospective observational study

Effect of neuromuscular blockage status on intraoperative MEPs monitoring during spinal surgery: A retrospective observational study - NARAMEDs Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000035799
Enrollment
160
Registered
2019-03-01
Start date
2019-03-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The condition required spinal surgery

Interventions

None listed

Sponsors

MSD Japan K.K.
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Patients aged 20-85 years between April 2013 and March 2018 2) Patients who underwent myogenic MEPs monitoring under total intravenous anesthesia during spinal surgery (corrective fixation of scoliosis, spinal tumor removal, laminoplasty, posterior fusion, fenestration, etc.) 3) Patients receiving rocuronium at the time of tracheal intubation 4) Patients whose TOF ratio was measured by EMG at the same time as MEPs monitoring

Exclusion criteria

Exclusion criteria: 1) Patients receiving the following medications known to affect neuromuscular function - Anti-epileptic drug - Oral steroid

Design outcomes

Primary

MeasureTime frame
TOF ratio Successful initiation of MEP MEP amplitude Effect on MEP amplitude amplification

Countries

Japan

Contacts

Public ContactTakashi SATO

IQVIA Services Japan K.K. Real World and Late Phase Research

JPRWESeRWEDATABASEREGISTRATION@iqvia.com03-6859-9500

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026