Effect of the supplement on accommodation of the eye in middle- and old-aged adults: A randomized, double blinded, placebo controlled, and parallel group comparison study.

Effect of the supplement on accommodation of the eye in middle- and old-aged adults: A randomized, double blinded, placebo controlled, and parallel group comparison study. - Effect of the supplement on accommodation of the eye in middle- and old-aged adults

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000035766

Enrollment

100

Registered

2019-02-04

Start date

2019-02-04

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults

Interventions

Ingestion of the test food for 4 weeks Ingestion of the placebo for 4 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Japanese male and female aged 35 to 65 years old at the time of the informed consent. 2. Subject who has no eye diseases other than refractive error (dysregulation). 3. Subject whose naked vision for each eye is more than 0.2. 4. Subject who has understood the purpose of the study, and agreed to participate it by signing the written informed consent.

Exclusion criteria

Exclusion criteria: 1. Subject who is taking medication or under medical treatment. 2. Subject who is under exercise therapy or dietetic therapy. 3. Subject who has an allergy for test food. 4. Subject who has or had a history of either medicine or alcohol dependence syndrome. 5. Subject who has or had a history of mental illness (depression) or sleep disturbance. 6. Subject who is on a night-shift or is a shift worker. 7. Subject whose lifestyle is extremely irregular. 8. Subject who has an unbalanced diet. 9. Subject who has or had a history of disease in liver, kidney, cardiovascular system, gastrointestinal, lung, blood or metabolic function. 10. Subject who has or had a history of eye disease (Not include minor eye diseases). 11. Subject who can stop taking any kind of health food, supplement or medicine other than the test foods during the current study. 12. Subject who has participated in other clinical studies within the past 3 months from the day of the consent acquisition or who is planning to participate in other clinical studies during the current study. 13. Subject who has blood drawn 200mL within the past 1 months or 400mL within the past 3 months from the day of the consent acquisition. 14. Subject who is planning to get pregnant after the day of informed consent or is currently pregnant and lactating. 15. Subject who can't keep the daily records. 16. Subject who is judged as an inappropriate candidate according to the screening data. 17. Subject who is considered as an inappropriate candidate by the doctor in charge.

Design outcomes

Primary

Measure	Time frame
Accommodation of the eye	—

Countries

Japan

Contacts

Public ContactMasao Matsuoka

HUMA R&D CORP Clinical Development Division

matsuoka@huma-rd.co.jp03-3431-1260

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026