Cognitive impairment
Conditions
Interventions
Period of intervention 12 weeks, Health Supplement Cordyceps, Intake twice a day after dinner in the morning and evening
Sponsors
University of Shizuoka
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) A person have mild cognitive decline: MMSE score 20-27 point 2) Prior to the research participation, the applicant and the person in charge of the document have obtained consent from the documents. 3) Age is 60 years old or older 4) A person who can cooperate in the intake and investigation of 12-week trial food 5) A person who can forbid the intake of supplements that affect the cognitive function one week before intake and during the intake period
Exclusion criteria
Exclusion criteria: 1)A person who are allergic to cordyceps or silk or mushrooms 2) A person who has severe cardiac or and liver or renal function decline 3) A person who is taking dementia treatment drugs 4) A person who is given priority in drug treatment or surgical treatment as a cause of cognitive decline 5) A person who is judged unfit by the physician in charge of this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes of mini-mental state examination (MMSE) score | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)Changes in domain of MMSE score 2)Changes of oxidative stress, inflammatory, dementia related markers 3)Changes of behavioral and psychological symptoms of dementia (BPSD) 4)Changes of quality of life (QOL) | — |
Countries
Japan
Contacts
Public ContactHiroshi Yamada
University of Shizuoka School of Pharmaceutical Sciences
Outcome results
None listed