Multimodality medical imaging analysis for bone/frailty-brain crosstalk

Multimodality medical imaging analysis for bone/frailty-brain crosstalk - Imaging study on bone/frailty-brain crosstalk

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000035762

Enrollment

500

Registered

2019-02-05

Start date

2018-07-11

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoporosis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients who measured Dual-energy X-ray Absorptiometry(DXA) scan. 2) Age over 49 years old in both men and women.

Exclusion criteria

Exclusion criteria: 1) Patients who have already been participated in other research studies. 2) Patients who has a medical history of musculoskeletal, parathyroid, psychological disorders and brain tumors. 3) Contraindication to undergoing MRI scan.

Design outcomes

Primary

Measure	Time frame
Mini-mental state examination (MMSE) scores.	—

Secondary

Measure	Time frame
Hand grip, muscle mass, gait parameters (walking speed, cadence, acceleration), blood exam, Areas related to cognitive impairment on brain MRI and SPECT-rCBF. Blood and/or cerebrospinal fluid specimens are stocked for further genomic analysis only after the patients' approval.	—

Countries

Japan

Contacts

Public ContactYasuko Tatewaki

Institute of Development, Aging and Cancer, Tohoku University Department of Nuclear Medicine and Radiology

ysktate@yahoo.co.jp022-717-8559

Outcome results