advanced cancer
Conditions
Interventions
Sponsors
Wakayama Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients who are diagnosed with advanced cancer. 2. ECOG PS 3/4 3. Patients who have dyspnea of 3 or more in NRS. 4. Patients with PaO2 <= 60 Torr or SpO2 <= 90%. 5. Patients who are more than 20 years old at the time of the informed consent. 6. Patients who agree to participate in the study with the written informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients who need 8 or more opioid rescue use per day. 2. Patients who plan artificial respiration management. 3. Patients who already have used HFNC. 4. Patients who have disturbance of consciousness of 12 or less GCS. 5. Patients under sustained sedation. 6. Patients with cognitive impairment or mental disorder who are regarded as inadequate to evaluate for the study by the investigators. 7. Patients who have participated in the other study at the time of the informed consent, or will participate in the other study. 8. Any other cases who are regarded as inadequate for the study enrollment by the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change amount of modified Borg scale at the start of treatment 24hours | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Change amount of modified Borg scale 2. Change amount of comfort(Numerical Rating Scale) 3. Respiratory rate 4. Implementention rate of medical therapy 5. SpO2 6. Glassgow Coma Scale 7. Completion rate of treatment | — |
Countries
Japan
Contacts
Public ContactShunsuke Teraoka
Wakayama Medical University Third Department of Internal Medicine
Outcome results
None listed