The effect of gut microbiota on the response to neoadjuvant DCF therapy for locally advanced esophageal cancer: A single center prospective study

The effect of gut microbiota on the response to neoadjuvant DCF therapy for locally advanced esophageal cancer: A single center prospective study - The effect of gut microbiota on the response to neoadjuvant DCF therapy for locally advanced esophageal cancer: A single center prospective study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000035732

Enrollment

Registered

2019-02-07

Start date

2019-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

esophageal cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1)undergoing neoadjuvant chemotherapy (2)curative intent surgery can be performed

Exclusion criteria

Exclusion criteria: (1)unable to join due to his/her mental status or metal disorder (2)attending doctors judge him/her to be inappropriate to join in this study

Design outcomes

Primary

Measure	Time frame
the transition of the microbiota of the patients during neoadjuvant chemotherapy.(before chemotherapy and after chemotherapy)	—

Secondary

Measure	Time frame
a. the difference of microbiota between patients who responded well to chemotherapy and patients who did not respond. b.the difference of microbiota between patients who sufferd adverse effects and patients who did not suffer them.	—

Countries

Japan

Contacts

Public ContactRaito Asaoka

Graduate School of Medicine, The university of Tokyo Department of gastrointestinal Surgery

raito.asaoka@icloud.com+81-3-3815-5411

Outcome results