N/A(healthy adults)
Conditions
Interventions
Oral intake of the test product (2 capsules one time in a day
Sponsors
TES Holdings Co., Ltd.
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: [1]Japanese females aged 40-59 years. [2]Individuals who are healthy and have no chronic physical disease including skin disease. [3]Individuals who are concerning on skin sagging and dullness. [4]Individuals whose written informed consent has been obtained. [5]Individuals who can have an examination in a designated day. [6]Individuals judged appropriate for the study by the principal.
Exclusion criteria
Exclusion criteria: [1]Individuals using medical products. [2]Individuals with skin disease, such as atopic dermatitis. [3]Individuals with strange skin conditions at measurement points. [4]Individuals who used or applied a drug for treatment of disease in the past 1 month. [5]Individuals who have a history of serious hepatopathy, kidney damage, heart disease, hematological and blood disease. [6]Individual who have digestive organ disease. [7]Individuals with serious anemia. [8]Individuals who are sensitive to test product or other foods, and medical products. [9]Individuals who are or are possibly pregnant, or are lactating. [10]Individuals who have an addiction to alcohol or a mental illness. [11]Individuals who are a smoker. [12]Individuals with possible changes of life style during the test period. [13]Individuals with probable seasonal allergy during the test period. [14]Individuals who have severe menopausal symptoms. [15]Individuals who neglect skin care. [16]Individuals who cannot avoid daylight exposure during the test period. [17]Individuals who had a habit to ingest health-promoting foods, foods for specified health uses, health foods, or supplements containing components of the test product in the past 3 months or will ingest those foods during the test period. [18] Individuals who had a habit to ingest health-promoting foods, foods for specified health uses, health foods, or supplements in the past 3 months or will ingest those foods during the test period. [19]Individuals who have a habit to use drug claiming to improve skin condition in the past 3 months. [20]Individuals who had been conducted an operation on the test spot. [21] Individuals who have a habit to use drug claiming to improve skin condition in the past 3 months. [22]Individuals judged inappropriate for the study by the principal.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| [1]Skin viscoelasticity (Week 0, Week 4, Week 8). | — |
Secondary
| Measure | Time frame |
|---|---|
| *Secondary indexes [1]Skin moisture content (Week 0, Week 4, Week 8). [2]Transepidermal water loss (Week 0, Week 4, Week 8). [3]Observation for skin condition by dermatologists (Week 0, Week 4, Week 8). [4]Arterial pressure-volume index, arterial velocity pulse index (Week 0, Week 4, Week 8). [5]Questionnaire of physical feeling (Week 0, Week 4, Week 8). *Safety [1]Weight, body fat percentage, BMI (Week 0, Week 4, Week 8). [2]Doctor's questions (Week 0, Week 4, Week 8). *Other index [1]Subject's diary (each day during the test period). | — |
Countries
Japan
Contacts
Public ContactRyoma Shimizu
TES Holdings Co., Ltd. Administrative Department of Clinical Trials
Outcome results
None listed