Healthy
Conditions
Interventions
Supplement(3capsule a day)
Placebo Supplement(3capsule a day)
Sponsors
Clinical Creative Corporation
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Age:40 years of age or 69 years of following a healthy Japan's men and women(at the time of obtaining informed consent) 2.hospitalization,outpatient:foreign 3.knee joint range of motion test persons evaluated in(goniometer)is bad 4.JKOM knee joint pain questionnaire is based on the person of low value(in principle 45 or less points) 5.JOA score is used as a reference person(with the exception of 70 points or more but 100 points)highs 6.Ability to consume test food for 12 weeks 7.If you are doing diet therapy or exercise therapy,those who do not change during the examination period 8.Those who can obtain written consent
Exclusion criteria
Exclusion criteria: 1.Persons who have excessive smoking or drinking habits 2.Alcohol or drug addiction 3.Those who performed knee surgery in the past 4.Those who need hospitalization and treatment due to knee joint pain 5.Persons who have received medical treatment(massage or electric therapy)at the medical institution within the past two weeks and are planned to complete the examination 6. Person who regularly uses general commercial externally applied agent(vantelin etc.),knee supporter,taping,poultice etc,for knee joint pain 7.While taking drugs for treatment of diseases,or those using injections,suppositories,etc. 8.Persons who have chronic diseases or disorders of liver,biliary tract,digestive system,cardiovascular system,respiratory system,kidney,urinary system,psychosis,nervous system,and blood system 9.Persons with arrhythmia and advanced anemia 10.Those who have the possibility of major changes in lifestyle during the examination period(including overseas trips) 11.Those who may be pregnant or may be pregnant,and those who are breastfeeding 12.One who has participated in other clinical trials within one month before acquiring consent or who is currently participating in other clinical trials 13.Person who is judged by the examination responsible physician or exam sharing doctor to increase the risk to the research subject by the examination or judge that there is a possibility that sufficient data can not be obtained
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| .JKOM(VAS including)knee joint pain questionnaire .JOA survey .Evaluation of flexion and extension degree of knee joint range of motion inspection by the goniometer .High sensitivity CRP .including doctors findings and evaluation (the subject diary) | — |
Secondary
| Measure | Time frame |
|---|---|
| .safety assessment .Blood,blood pressure,body weight Safety:vital signs,hematology,blood biochemistry,urinalysis,adverse events,and other associated symptoms .Subject diary | — |
Countries
Japan
Contacts
Public ContactHideki Hokazono
Sanwa Shurui Co.,Ltd. Food Division Functionality Laboratory
Outcome results
None listed