Discovering immune complex antigen specific for oral cancer in saliva

Discovering immune complex antigen specific for oral cancer in saliva - Immune complex antigens in oral cancer

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000035607

Enrollment

210

Registered

2019-02-01

Start date

2018-09-11

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oral cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. License date of the chief of the research institution - March 31, 2021, a hospital participating in Oral Surgery at Nagasaki University Hospital and Japan Oral Oncology Group (NPO) patient. 2. Target diseases: patients with oral cancer and patients with xerostomia (the standard of xerostomia is 2 g / 2 minutes or less in Saxon test saliva secretion) 3. Age: over 20 years old 4. Gender: male / female 5. Patient who obtained written agreement with the free will of the research subject himself after sufficient explanation for participation in this research.

Exclusion criteria

Exclusion criteria: 1. Patients who are judged inappropriate as researchers by the researchers.

Design outcomes

Primary

Measure	Time frame
We analyze immune complex in saliva and identify antigen protein that is not recognized in patients with xerostomia and is specifically detected in oral cancer patients. In addition, we investigate whether specific ones of the antigen proteins are characteristic of patients who have cervical lymph node metastasis or distant metastasis.	—

Countries

Japan

Contacts

Public ContactKaname Ohyama

Nagasaki University Graduate School of Biomedical Sciences

k-ohyama@nagasaki-u.ac.jp095-819-8569

Outcome results