None (Healthy adults)
Conditions
Interventions
Supplementation of test food 3 capsules a day, 12 weeks
Supplementation of placebo 3 capsules a day, 12 weeks
Sponsors
TTC Co.,Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Subjects who fall under all of the following (1) to (6) (1) Men and women aged from 45 to 69 (2) Subjects whose primary language is Japanese (3) Subjects with self-awareness of decline of the brain or forgetfulness (4) Subjects who often forget the name of people or objects (5) Subjects who often carelessly make mistakes in daily life (6) Subjects whose subjective cognitive function declines have been confirmed by questionnaires
Exclusion criteria
Exclusion criteria: Subjects (1)whose visual acuity is too low to perform test (2)whose hearing acuity is too low to perform test (3)whose score of the MMSE is 23 or less (4)who have anamnesis of cranial nerve disease (5)who have depressive symptoms, or have been diagnosed as depressive disorder (6)who are being treated with hormone, or have been diagnosed as menopausal symptoms (7)who have irregular lifestyles during the study (8)who regularly take too much alcohol drink (9)who regularly smoke or subjects who started smoking cessation within 1 year (10)who have taken the similar cognitive tests within 1 year (11)who are being treated for cognitive functions, or prescribed drugs associated with cognitive functions (12)who suffer from sleep related diseases, or are conscious of it (13)who are diagnosed with arrhythmias or xerostomia (14)who have troubles in the mouth, those who develop at least once a week (15)who regularly take drugs or health foods which may affect this study more than once a week (16)who regularly take foods similar to test foods more than once a week (17)who regularly take energy drinks more than once a week (18)who have done blood transfusion or blood donation within 3 months (19)who have participated in other clinical studies within 1 month, or are planning to participate in other clinical studies during this study (20)who have diseases requiring regular administration, or have severe diseases (21)who are judged as unsuitable for laboratory value, anthropometric measurements, or physical examination value (22)who have allergy to test foods (23)who are, or are planning to be pregnant or breastfeeding during study (24)who are judged as unsuitable due to lifestyle questionnaire (25)who and whose family work in a company developing functional foods (26)who are judged as unsuitable by doctor for other reasons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tests for cognitive functions | — |
Secondary
| Measure | Time frame |
|---|---|
| Autonomic nervous activity Biochemical examination in saliva Biochemical examination in blood Questionnaires | — |
Countries
Japan
Contacts
Public ContactIsobe Kotoha
TTC Co.,Ltd. Clinical Research Planning Department
Outcome results
None listed