N/A (Healthy adults)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: [1]Males and Females aged 20> years. [2]Those who are conscious of coldness of 4 points or more (Important item; 2 point, Reference item 1 point) in coldness diagnosis questionnaire [3] Those whose skin temperature recovery rate is less than 90% after 10 minutes of cold load in skin temperature recovery rate measurement [4] Those who obtain consent from the document with free will of the subject
Exclusion criteria
Exclusion criteria: [1]Those who are at risk of developing allergy in connection with research [2]Those who have been diagnosed as underlying diseases associated with vascular disorders (obstructive arteriosclerosis, obstructive arteritis, collagen disease, diabetes etc.) [3]Those who were judged inappropriate as subjects from the answers to the questionnaire [4]Those who have a smoking habit [5]Those who regularly use prescribed medicines (eg, warfarin, etc.) that may affect blood flow and skin surface temperature [6]Those who take foods for specified health use or health foods that affect blood flow and skin surface temperature for three days or more per week [7]Those already taking citrus drinks such as shikuwasa and oranges more than 3 days a week [8]Those who were judged to have problems with research participation due to abnormalities in clinical laboratory values or cardiorespiratory functions [9]Those who have a disease requiring continuous medication, those who have had a serious medical history requiring medication therapy [10]Persons whose values of physical measurement values, physical examination values and clinical laboratory values before the start of ingestion are significantly deviated from the reference range [11]Those who participate in other clinical research at the start of this research [12]Others who judged that the researcher is inappropriate as the subject
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| [1]Skin surface temperature | — |
Secondary
| Measure | Time frame |
|---|---|
| [1]Peripheral blood flow | — |
Countries
Japan
Contacts
Okinawa TLO Co., Ltd. Not Division