Risk stratification in Brugada syndrome: analysis of unipolar Holter electrocardiogram after Pilsicainide provocation.

Risk stratification in Brugada syndrome: analysis of unipolar Holter electrocardiogram after Pilsicainide provocation. - Unipolar Holter electrocardiogram after Pilsicainide provocation in Brugada syndrome.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000035530

Enrollment

Registered

2019-01-12

Start date

2018-10-02

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brugada syndrome

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Consecutive patients who with Brugada syndrome

Exclusion criteria

Exclusion criteria: 1) Patients with bundle branch block. 2)Patients with left ventricular dysfunction and/or structural heart diseases. 3) Patients who have an invasive therapy for other disease. 4) Patients who cannot undergo Holter ECG. 5) Patients who rejected the inclusion in this study.

Design outcomes

Primary

Measure	Time frame
To evaluate late potentials [LP: filtered QRS(f-QRS), duration of low-amplitude signals :LAS40 and root mean square voltage:RMS40], ST amplitude(mV), QTc interval, J amplitude and T-wave alternans (TWA) in leads V2 and V5 on unipolar Holter electrocardiogram after the plisicainide provocation.	—

Countries

Japan

Contacts

Public ContactMasahiko Takagi

Kansai Medical University Department of Medicine 2

takagims@takii.kmu.ac.jp(06)6992-1001

Outcome results