Acute Heart Failure
Conditions
Interventions
None listed
Sponsors
Department of Cardiovascular Medicine, Juntendo University
Kobe City Medical Center General Hospital, Kameda General Hospital, Tokai University, Toho University Omori Medical Center, Musashino Red Cross Hospital, Hamamatsu University School of Medicine, Yokohama Southern Kyosai Hospital, The University of Tokyo, Iwate Medical University, Tokyo Medical and Dental University (TMDU), Teikyo University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients diagnosed as acute heart failure fulfilling all the below criteria - Dyspnea at rest or mild exertion - Age equal or above 20 - Show at least one sign of congestion inclusion peripheral edema, rale, JVD, congestion shown by chest Xp) - BNP >=100 pg/mL or NT-proBNP >=300 pg/mL 2) Prescribed at least 10mg oral furosemide at the time of admission 3) Needs treatment with iv furosemide 4) Expected to use urinary catheter at least 6 hours 5) Those who are not obviously inappropriate
Exclusion criteria
Exclusion criteria: 1) eGFR <15 mL/min/1.73m2 2) Cardiogenic shock 3) acute myocarditis, post heart transplantation, needs mechanical circulatory support 4) Already treated with iv furosemide before enrollment 5) Need emergent revascularization with 6) Need treatment with carperitide within 6 hours 7) No consent achieved
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Urinary sodium excretion achieved within 6 hours 2. 180-day all-cause mortality | — |
Countries
Japan
Contacts
Public ContactTakeshi Kitai
Kobe City Medical Center General Hospital Department of Cardiovascular Medicine
Outcome results
None listed