Efficacy of preemptive inferior mesenteric artery embolization during endovascular aortic aneurysm repair

A multicenter randomized controlled trial to evaluate the efficacy of preemptive inferior mesenteric artery embolization during endovascular aortic aneurysm repair on aneurysm sac change: Clarify IMA - Clarify IMA

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000035502

Enrollment

200

Registered

2019-02-01

Start date

2019-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abdominal aortic aneurysm

Interventions

Preemptive embolization of IMA during EVAR Control

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Aneurysm sac diameter >50mm or sac with rapid enlargement IMA diameter >2.5mm Age >20yo Anatomical limitation of proximal neck as the followings Diameter <28mm Length >15mm Infrarenal angulation <60 degree (If possible)

Exclusion criteria

Exclusion criteria: IMA diameter <2.5mm or occluded/stenotic orifice IMA originates from the proximal neck Under treatment for advanced malignant tumor Life expectancy<1 year Connective tissue disease such as Marfan syn.or Ehlers-Danlos syndrome Mycotic aneurysm Saccular aneurysm/ PAU(penetrating atherosclerotic ulcer) Allergy for contrast media Preoperative eGFR<30ml/dl and has not introduced hemodialysis Pregnancy Younger than 20 yo

Design outcomes

Primary

Measure	Time frame
Comparison of aneurysm sac change in both arms at 12M after EVAR	—

Secondary

Measure	Time frame
Rate of persistent type II endoleak at 6,12,24M Comparison of aneurysm sac change and sac diameter change in both arms at 6,12,24M after EVAR Rate of freedom from reintervention Rate of freedom from aneurysm related death Volume of contrast media usage Radiation exposure Device cost	—

Countries

Japan,Europe

Contacts

Public ContactShigeo Ichihashi

Nara Medical University Radiology

ichihash@naramed-u.ac.jp+81744298900

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026