Diabetes improvement effect by full mouth SRP combined with antibiotics for diabetes patient with periodontal disease.

Diabetes improvement effect by full mouth SRP combined with antibiotics for diabetes patient with periodontal disease. - The effects of periodontal pharmacotherapy on diabetes.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000035472

Enrollment

120

Registered

2019-01-10

Start date

2019-01-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic periodontitis

Interventions

Azithromysin duration of administration: 1time/day, for 3 days Dosage: 500mg/time Full mouth SRP

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: *Age 35 years old or older * The residual teeth more than 10 teeth *Periodontal pockets 4mm or more have more than 30%

Exclusion criteria

Exclusion criteria: *Person with a serious systemic disease except the diabetes mellitus *The allergy to a macrolide derivative antimicrobial agent *Smokers *Person who dentist judged inadequate

Design outcomes

Primary

Measure	Time frame
PISA (Periodontal inflamed surface area) time of assesment after 1, 3, 6 month, 1, 2 year from the start of the study.	—

Secondary

Measure	Time frame
periodontal pocket depth, BOP, HbA1c, hs-CRP, IL-6, MCP-1	—

Countries

Japan

Contacts

Public ContactKazuhiro Gomi

Tsurumi University, School of Dental Medicine Department of Periodontology

gomi-k@tsurumi-u.ac.jp045-580-8431

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026