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Contamination of blood cultures from arterial catheters vs peripheral venipuncture in critically ill patients: A multicenter prospective observational study

Contamination of blood cultures from arterial catheters vs peripheral venipuncture in critically ill patients: A multicenter prospective observational study - Contamination of blood cultures from arterial catheters (CONTACT study)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000035392
Enrollment
590
Registered
2018-12-29
Start date
2018-12-29
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Suspected bacteremia in adult critically ill patients

Interventions

None listed

Sponsors

Okinawa Chubu Hospital, Intensive Care Unit
Lead Sponsor
Sakai City Medical Center Kameda General Hospital Musashino Red Cross Hospital Kobe City Medical Center General Hospital
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Blood cultures collected during clinically suspected episodes of bacteremia AND 1. Obtained from adult (20 years or older) critically ill patients 2. A paired blood culture sets, consisting of one blood culture set drawn from existing arterial catheters and one blood culture set drawn from peripheral skin punctures. All blood cultures obtained from adult critically ill patients will be screened for eligibility during the study period. All consecutive blood culture sets will be enrolled if they fulfill the inclusion criteria and none of the exclusion criteria.

Exclusion criteria

Exclusion criteria: 1. Obtained from arterial lines without a closed blood sampling system 2. Percutaneous procedures (PCI, IVR) had performed through the arterial line 3. Inappropriately labeled blood cultures 4. Enrolled in this study previously 5. Refusal of study participation

Design outcomes

Primary

MeasureTime frame
The proportions of blood culture contamination Assessment of the primary outcome: every positive blood culture will be evaluated with two staff infectious disease specialists who will be blinded to the source of the blood culture (arterial catheters or skin puncture).

Secondary

MeasureTime frame
The volumes of collected blood; the sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, positive predictive value and negative predictive value of true bacteremia

Countries

Japan

Contacts

Public ContactIzumi Nakayama

Okinawa Chubu Hospital Intensive Care Unit

izunakayama-circ@umin.org098-973-4111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026