Relationship between post-stroke fatigue and autonomic nerve function: a fundamental research to develop an effective treatment for post-stroke fatigue

Relationship between post-stroke fatigue and autonomic nerve function: a fundamental research to develop an effective treatment for post-stroke fatigue - Autonomic nerve function in individuals with post-stroke fatigue

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000035327

Enrollment

100

Registered

2018-12-21

Start date

2019-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. First-ever stroke 2. Stroke within 1 to 6 months 3. Unilateral hemiparetic stroke 4. No severe cognitive impairment (a Mini-mental State Examination score of 24 or more) 5. Age between 40 and 80 years 6. Able to stand up without manual assistance 7. Consent to participate in this study

Exclusion criteria

Exclusion criteria: 1. Arrhythmia such as atrial fibrillation 2. Cognitive impairment leading to inability to cooperate 3. Using a cardiac pacemaker 4. A heart rate of more than 120 bpm or a systolic blood pressure of less than 90 mmHg during supine at rest 5. Other neurologic conditions in addition to stroke

Design outcomes

Primary

Measure	Time frame
Heart rate variability	—

Secondary

Measure	Time frame
The number of postural orthostatic tachycardia syndrome The number of orthostatic hypotension The number of neurally mediated hypotension Changes in heart rate during a conventional active standing test Changes in blood pressure during a conventional active standing test	—

Countries

Japan

Contacts

Public ContactKeita Sue

Kakeyu-Misayama rehabilitation center Department of Physical Therapy

keitasue@live.jp0268-44-2111

Outcome results