Dental pulp wound healing and repair mechanism in vital pulp therapy - Investigation by immunohistochemistry and gene expression analysis -

Dental pulp wound healing and repair mechanism in vital pulp therapy - Investigation by immunohistochemistry and gene expression analysis - - Dental pulp wound healing and repair mechanism in vital pulp therapy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000035318

Enrollment

Registered

2018-12-20

Start date

2016-04-28

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental caries

Interventions

Application of 3Mix to indirect pulp capping of deep caries Application of Mineral Trioxide Aggregate (MTA) to indirect pulp capping of deep caries Untreated carious teeth

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Dental caries diagnosed as extraction for orthodontic treatment.

Exclusion criteria

Exclusion criteria: Patients who have severe systemic diseases. Tooth with severe periodontitis. Non-vital tooth.

Design outcomes

Primary

Measure	Time frame
Inflammatory cell infiltration and reparative dentin formation up to 3 months after treatment	—

Countries

Japan

Contacts

Public ContactNagako Yoshiba

Niigata University Medical and Dental Hospital

nagako@dent.niigatau.ac.jp025-227-2866

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026