Effect of oxytocin nasal spray on auditory automatic discrimination measured by mismatch negativity in schizophrenia

Effect of oxytocin nasal spray on auditory automatic discrimination measured by mismatch negativity in schizophrenia - Effect of oxytocin nasal spray on auditory automatic discrimination measured by mismatch negativity

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000035302

Enrollment

Registered

2018-12-19

Start date

2016-06-08

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

schizophrenia

Interventions

Single administration of 24 IU of oxytocin nasal sprays to schizophrenia. Single administration of 24 IU of placebo nasal sprays to schizophrenia. Single administration of 24 IU of oxytocin nasal sp

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients were diagnosed Schizophrenia in DSM-5 (Diagnostic and Statistical Manual of Mental Disorders), which was thought to be able to fully understand the contents of the experiment and its significance.

Exclusion criteria

Exclusion criteria: Exclusion criteria were epilepsy, mental retardation, a history of hypersensitivity to Oxytocin, drug abuse / dependence, continuous administration of Oxytocin, pregnancy, and a history of psychiatric or neurological disorders.

Design outcomes

Primary

Measure	Time frame
Mismatch negativity(MMN)	—

Secondary

Measure	Time frame
Facial Emotion Selection Test(FEST)	—

Countries

Japan

Contacts

Public ContactOchiai Haruka

Fukushima Medical University Department of Psychiatry

haruka-o@fmu.ac.jp0245471331

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026