Portal hyperternsion related UGI bleeding
Conditions
Interventions
After variceal band ligation, Patient in PPI and sucralfate group will be given Tab Pantoprazole 40 mg twice daily for 14 days along with syrup Sucralfate 10ml four times daily for next two weeks.
Aft
Sponsors
Bir Hospital National Academy of Medical sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Patients with chronic liver disease who undergo esophageal variceal banding
Exclusion criteria
Exclusion criteria: 1. Patients presenting with fundal varices. 2. Patients who had been subjected to injection sclerotherapy sessions or having endoscopically confirmed pre-existing oesophageal ulcers. 3. Patients with co- morbidities like diabetes, bleeding disorders, heart failure, chronic kidney disease and malignancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the outcomes of variceal band ligations in patients receiving Sucralfate plus PPI vs PPI alone. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) To find out the incidence of EVL ulcers in both the groups. 2) To find out the number and mean size of EVL in both the groups within two weeks. 3) To find out the incidence of EVL bleeding or death due to any cause within two weeks of the procedure. 4) To find out the effect of Child-Pugh score and incidence of ulcer formation in both the groups. | — |
Countries
Asia(except Japan)
Contacts
Public ContactBinod Karki
Bir Hospital National Academy of Medical sciences Gastroenterology
Outcome results
None listed