Clinical trial on the efficacy on the wrinkle conforming to the guideline of Japanese Cosmetic Science Society

Clinical trial on the efficacy on the wrinkle conforming to the guideline of Japanese Cosmetic Science Society - Clinical trial on the efficacy on the wrinkle conforming to the guideline of Japanese Cosmetic Science Society

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000035286

Enrollment

Registered

2018-12-19

Start date

2018-12-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy volunteer

Interventions

Apply the test cosmetic product to the designated left or right half face. Apply the placebo cosmetic product to the designated left or right half face.

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1) Healthy women aged 30 to 59 years old at the time of acquisition. 2) Individuals who are healthy and are currently not treating with any disease. 3) Individuals who have wrinkles of grade 3 to 5 in the outer corner of the eyes. 4) Individuals who obtained the written consent to participate in the study after explanation of the details of the study and understanding it sufficiently

Exclusion criteria

Exclusion criteria: 1) Individuals who have a history of allergy to cosmetics. 2) Individuals undergoing hormone replacement therapy. 3) Individuals who are pregnant or lactating. 4) Individuals who have experienced cosmetic care that will affect the test site. 5) Individuals who acknowledge that doctors involved in the examination are not appropriate.

Design outcomes

Primary

Measure	Time frame
Visual evaluation of wrinkle grade	—

Countries

Japan

Contacts

Public ContactYuki Yamashita

Nikoderm Research Inc. Evaluation Division

yamashita@nikoderm.com06-6125-3501

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026