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Efficacy of medication optimization protocol for older inpatients: a randomized controlled trial

Efficacy of medication optimization protocol for older inpatients: a randomized controlled trial - Efficacy of medication optimization protocol for older inpatients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000035265
Enrollment
500
Registered
2018-12-21
Start date
2019-03-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polypharmacy among older adults

Interventions

A multidisciplinary team-based medication review and deprescribing proposal based on STOPP/START criteria and a medication optimization protocol. Usual care

Sponsors

St. Marianna university school of medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Patients admitted to the internal medicine department of Kawasaki Municipal Tama Hospital (general internal medicine, gastroenterology, cardiology, respiratory medicine, endocrinology, nephrology, and neurology) 2) Patients aged 65 years or older at the time of enrollment 3) Patients who are confirmed to have 5 or more regular medications at the time of admission 4) Patients with expected hospitalization duration of 1 week or longer 5) Patients who are permitted to be given oral medication by the attending physician at the time of the trial participation 6) Patients with written agreement for study participation by themselves or by the substitute person with sufficient understanding

Exclusion criteria

Exclusion criteria: 1) Patients whose attending physician do not agree to participate in the study

Design outcomes

Primary

MeasureTime frame
Composite of death, unscheduled visits, and re-hospitalization until 12 months after randomization.

Countries

Japan

Contacts

Public ContactSatomi Tsuchiya

Kawasaki Municipal Tama Hospital General Affairs Section

s-tsuchiya@marianna-u.ac.jp044-933-8111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026