A study for gene polymorphisms related to wheat allergy

A study for gene polymorphisms related to wheat allergy - A study for gene polymorphisms related to wheat allergy

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000035250

Enrollment

400

Registered

2018-12-14

Start date

2018-10-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Wheat allergy

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients who meets the following diagnostic criteria will be enrolled: the diagnostic criteria of wheat-dependent exercise-induced anaphylaxis made by study group of Guideline for the treatment of life-threatening food allergy, supported by Health and Labor Sciences Research Grant; Patients who have immediate allergic reactions to wheat after ingestion of wheat product, and have the positive reaction of serum wheat related antigen-specific IgE. 2. The age at the time of consent is 20 years old or over. 3. Agreement has been obtained from the principal concerning research participation in writing.

Exclusion criteria

Exclusion criteria: No exclusion criteria

Design outcomes

Primary

Measure	Time frame
To identify a specific maker SNP aggregated in patients with wheat allergy by comparing whole genome SNP information of wheat allergy patients and sample Japanese population. Polymorphism analysis will be carried out for several genes present in the gene region where the marker exists. Further we will conduct an association analysis using a database of sample Japanese population and identify genes related to wheat allergy.	—

Measure

Time frame

To identify a specific maker SNP aggregated in patients with wheat allergy by comparing whole genome SNP information of wheat allergy patients and sample Japanese population. Polymorphism analysis will be carried out for several genes present in the gene region where the marker exists. Further we will conduct an association analysis using a database of sample Japanese population and identify genes related to wheat allergy.

—

Countries

Japan

Contacts

Public ContactEishin Morita

Shimane University Faculty of Medicine, Department of Dermatology

ychinuki@med.shimane-u.ac.jp0853-20-2210

Outcome results