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A phase II clinical trial of neoadjuvant chemoradiation therapy for pancreatic ductal adenocarcinoma

A phase II clinical trial of neoadjuvant chemoradiation therapy for pancreatic ductal adenocarcinoma - A phase II clinical trial of neoadjuvant chemoradiation therapy for pancreatic ductal adenocarcinoma

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000035232
Enrollment
50
Registered
2018-12-12
Start date
2016-05-26
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pancreatic cancer

Interventions

To investigate the frequency of histological curative resection following chemoradiation using S1 combined with RT for resectable and borderline resectable (BR-PV) pancreatic ductal adenocarcinoma

Sponsors

Department of Gastroenterological Surgery, Faculty of Medicine, Kagawa University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Patients with radiologically defined patentially resectable pancreatic cancer 2) Patients who have not undergone radiotherapy to the abdomen 3) Patients who have not undergone chemotherapy within 6 months 4) Patients with Performance status of 0/1 5) Patients with sustained organ function 6) Patients who received informed consent

Exclusion criteria

Exclusion criteria: 1) Patients with other active cancers 2) Patients who can not take medicine orally 3) Patients with severe allergies 4) Patients with watery diarrhea 5) Patients with severe co-morbid disease 6) Patients seems inadequate for this study by investigator(s)

Design outcomes

Primary

MeasureTime frame
Histological curative resection (R0 ratio)

Secondary

MeasureTime frame
Pathological responce rate, Incident of adverse event, Overall survival, Relapse free survival

Countries

Japan

Contacts

Public ContactHironobu Suto

Faculty of Medicine, Kagawa University Gastroenterological Surgery

hsuto@med.kagawa-u.ac.jp087-898-5111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026