Healthy adults
Conditions
Interventions
Apply the model water based lotion and model lotion on facial skin for twice a day for a week. And apply the pseudo-ceramide containing formulation and model lotion on facial skin for twice a day f
skin for twice a day for 4 weeks.
Apply the model water based lotion and model lotion on facial skin for twice a day for a week. And apply the water based lotion on the market and model lotion on fac
skin for twice a day for 4 weeks.
Sponsors
Kao Corporation
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1.Healthy female aged from 20 to 49 years old. 2.Subjects who have sensitive and dry skin consciousness. 3.Subjects who can agree to participate in the study voluntarily in writing. 4.Subjects who can agree to change her currently-using cosmetics to designated ones during the test period.
Exclusion criteria
Exclusion criteria: 1.Subjects who has abnormalities in the skin of the measurement regions 2.Subjects who regularly goes to hospital. 3.Subjects with the anamnesis of an alcohol or a drug dependence. 4.Subjects who regularly use drugs (hypnotic drug, anti-allergic drug, analgetic drug, hormonal drug, laxative, antiflatulent etc...). 5.Subjects who has possibilities for emerging allergy to cosmetics and/or foods (including experiences of skin irritation by cosmetics within a year). 6.Subjects who has allergy to adhesive tape and/or medical tape. 7.Subjects who suffers pollen allergy, severe rhinitis and atopic dermatitis. 8.Subjects who is pregnant or lactating, or planned to become pregnant during a test period. 9.Subjects who participates in the other clinical studies within 4 weeks in the past, or person who scheduled to participate in other clinical studies during the test period. 10.Subjects who is judged as unsuitable for the study by the investigator for other reasons. 11.Subjects who herself and/or her family members are working for the cosmetics company, the food company, an advertising agency, investigation and consultant business, and a mass media-related company. 12.Person who experienced medical cosmetic treatments (i.e. cosmetic surgery, collagen injection etc..)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of the transepidermal water loss,after treatments for 4 weeks use with the pseudo-ceramide containing formulation | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of the stratum corneum water content,transepidermal water loss,sebum secretion,skin color,skin viscoelasticity,stratum corneum,dermatological assessment,a questionnaire survey and VAS after treatments for 4 weeks use with the pseudo-ceramide containing formulation | — |
Countries
Japan
Contacts
Public ContactDaisuke Watanabe
Kao Corporation R&D Skin Care Products Research
Outcome results
None listed