CKD stages G3-4 patients
Conditions
Interventions
Patients in the exercise group will undergo stretching, resistance, and aerobic training once a week at our rehabilitation center and more than twice a week at home for 24 weeks. The intensity will be
Sponsors
Kawasaki Municipal Tama Hospital Division of Nephrology and Hypertension, Department of Internal Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with CKD stages G3 and 4 (estimated glomerular filtration rate, 15-59 mL/min/1.73m2)
Exclusion criteria
Exclusion criteria: Gait assistance Dementia Receiving renal replacement therapy (RRT) Planning to undergo RRT in 6 months Arteriosclerosis obliterans with Fontaine classification stage 2 or higher Exercise restriction by a medical doctor Unstable angina pectoris Poorly controlled diabetes mellitus Inappropriate as participants judged by a medical doctor
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in cognitive (global cognition, several cognitive domains) evaluated after a 24-week intervention. | — |
Secondary
| Measure | Time frame |
|---|---|
| Physical (muscle strength, balance function, and gait speed) function, endothelial function, plasma brain-derived neurotrophic factor concentration, ADMA concentration, quality of life, depression status, and body composition evaluated after a 24-week intervention. | — |
Countries
Japan
Contacts
Public ContactYuhei Otobe
Kawasaki Municipal Tama Hospital Department of Rehabilitation medicine
Outcome results
None listed