A Prospective, Non-randomized, Multicenter Study of the Efficacy of Adhesion Barriers in Laparoscopic Surgery for Colorectal Cancer in Japan

A Prospective, Non-randomized, Multicenter Study of the Efficacy of Adhesion Barriers in Laparoscopic Surgery for Colorectal Cancer in Japan - SETOUCHI Study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000035144

Enrollment

1200

Registered

2018-12-17

Start date

2019-04-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal Cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients who are planned to laparoscopic resection of colorectal cancer. 2) PS: 0 to 2 (ECOG performance status score). 3) Patients who can agree to join this study by written consent. 4) Patients judged to be able to survive for more than 1 year from the date of registration.

Exclusion criteria

Exclusion criteria: 1) History of allergy for adhesion barriers 2) Cancerous ascites or peritoneal dissemination is observed on radiographic image 3) The attending physician deems inappropriate for participation in this study

Design outcomes

Primary

Measure	Time frame
Comparison of Incidence of adhesion-related complications observed in patients without adhesion prevention material with that of patients with adhesion prevention materials.	—

Secondary

Measure	Time frame
1) incidence of adhesion-related complications between anti-adhesion materials. 2) incidence of adhesion-related complications by adhesion preventing material spraying sites. 3) postoperative recurrence rate, relapse-free survival and overall survival of Stage II / III colorectal cancer after curative resection. 4) incidence of adhesion-related complications, postoperative recurrence rate, relapse-free survival , and overall survival of Stage II / III colorectal cancer after curative resection stratified by somatic mutation in colorectal cancer.	—

Measure

Time frame

1) incidence of adhesion-related complications between anti-adhesion materials. 2) incidence of adhesion-related complications by adhesion preventing material spraying sites. 3) postoperative recurrence rate, relapse-free survival and overall survival of Stage II / III colorectal cancer after curative resection. 4) incidence of adhesion-related complications, postoperative recurrence rate, relapse-free survival , and overall survival of Stage II / III colorectal cancer after curative resection stratified by somatic mutation in colorectal cancer.

—

Countries

Japan

Contacts

Public ContactTakeshi Nagasaka

Kawasaki Medical School Hospital Department of Clinical Oncology

takeshin@med.kawasaki-m.ac.jp086-462-1111

Outcome results