Pancreatic cancer
Conditions
Interventions
50 Gy/5 fractions of MR-guided online adaptive stereotactic body radiotherapy for pancreatic cancer
Sponsors
National Cancer Center Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Pathologically-proven pancreatic cancer N0-1M0 Unresectable tumor or refusal of surgery No carcinomatous pleural effusion or ascites PS 0-1 No active peptic ulcer No history of surgery for pancreatic tumor No history of radiotherapy to the pancreas 56 days or more after the start of standard chemotherapy for pancreatic cancer, or difficulty in continuing chemotherapy Normal organ functions by blood test Written informed consent
Exclusion criteria
Exclusion criteria: Active multiple primary cancer Infectious diseases requiring systemic treatment Fever of 38 degrees Celcius or higher Women with pregnancy, with possible pregnancy, during lactation, or within 28 days after giving birth, and men who expect the partner's pregnancy Psychiatric illness or psychological symptoms Other severe comorbidity Problems in taking MRI Unstable angina, or history of myocardial infarction within 6 months Contraindication to both contrast agents of iodinated and gadolinium-based, due to drug allergy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The feasibility of MR-guided stereotactic body radiotherapy for unresectable pancreatic cancer without distant metastasis | — |
Countries
Japan
Contacts
Public ContactHiroshi Igaki
National Cancer Center Hospital Department of Radiation Oncology
Outcome results
None listed