The Utility and Validity of Intracoronary Administration of Nicorandil Alone for the Measurement of Fractional Flow Reserve in Patients With Intermediate Coronary Stenosis

The Utility and Validity of Intracoronary Administration of Nicorandil Alone for the Measurement of Fractional Flow Reserve in Patients With Intermediate Coronary Stenosis - Intracoronary Nicorandil for the Measurement of Fractional Flow Reserve

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000035100

Enrollment

220

Registered

2018-12-01

Start date

2017-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Angina Pectoris

Interventions

2mg of intracoronary nicorandil continuous intravenous infusion of ATP 150microg/kg/min for 2 minutes continuous intravenous infusion of ATP 210microg/kg/min for 2 minutes 0.5mg of intracoronary nicor

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who have a 50 to 75% focal stenosis in the coronary artery on diagnostic coronary angiography

Exclusion criteria

Exclusion criteria: younger than 20 years old older than 80 years old acute coronary syndrome heart failure left main stenosis post coronary artery bypass graft

Design outcomes

Primary

Measure	Time frame
Reliability for FFR value after administration of each drug	—

Secondary

Measure	Time frame
The incidence of side effect for each drug	—

Countries

Japan

Contacts

Public ContactKenichi Fujii

Higashi Takarazuka Satoh Hospital Department of Cardiology

kfujii350@hotmail.com0797882200

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026