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Identification of effective morphine administration route for postoperative pain in robot-assisted rectal resection (prospective intervention, open label test)

Identification of effective morphine administration route for postoperative pain in robot-assisted rectal resection (prospective intervention, open label test) - Identification of effective morphine administration route for robot-assisted rectal resection

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000035096
Enrollment
48
Registered
2018-12-03
Start date
2018-12-02
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rectal cancer

Interventions

from POD 0 - POD 2 route of administration of morphine continuous epidural infusion (0.26 mg /day) from POD 0 - POD 2 iv-PCA(continuous infusion: none, bolus: 1 mg, lockout time: 15 min)

Sponsors

Sapporo Medical University School of Medicine Clinical Department
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: ASA-PS I-II

Exclusion criteria

Exclusion criteria: case of ASA-PS > III case of body weight < 40 kg case of BMI > 35 kg/m2 Bronchial asthma, emphysema complicated case Heart failure case Liver / kidney disfunction case ECG abnormal case (QT extension etc.) Patients with Parkinson's disease Alcohol and drug abuse history cases Cases with a history of allergy to morphine, local anesthetics and other analgesics Cases who consent can not be obtained

Design outcomes

Primary

MeasureTime frame
analgesia from postoperatve day(PID)0 to POD 2 pain score the consumption of morphine and additional analgesics recovery of bowel function from POD 0 to POD 2

Secondary

MeasureTime frame
adverse effects from POD 0 to POD 2 postoperative nausea and vomiting sedation respiratory defect patient's satisfaction at POD 1, 2 using QoR-40 sheets

Countries

Japan

Contacts

Public ContactYukitoshi Niiyama

Sapporo Medical University, School of Medicine Department of Anesthesiology

niiyama@sapmed.acjp011-611-2111(35680)

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026